I will also say that we do see pretty much every year a new "point of emphasis" given to referees and that usually DOES have a fairly pronounced impact.
For instance like I mentioned above with the Legion of Boom, I can't remember exactly - either 2013 or 2014 the league put out a notice to referees that the upcoming season's point of emphasis would be defensive holding/illegal contact. They started calling it a lot more tightly and the "Legion of Boom-style" defense pretty quickly became non-viable from then onward (to be fair some of that is just due to player moves, guys getting older, etc).
so while they might not change the way holding is written as a penalty or anything like that, if it becomes enough of an issue it may be an offseason point of emphasis in the near future.
BUT, that said, I don't expect much to change. We all know by now that the league feels (and probably rightly so) that generally good offense is better for viewership/ratings than defense. As such they are almost always going to err on the side of the offense's favor. To put it simply, the league HATES offensive holding penalties. Not even singling out Micah, it's just not something that is beneficial to their "product". It slows the game down dramatically, it extends drives (down repeated), and it lowers scoring probability. In fact, OPI is the only offensive penalty with a worse "hit" to an offense's EPA on a given play than offensive holding...but when you consider the frequency at which these penalties are called (Offensive holding is called roughly 5x more frequently than OPI), offensive holding is by FAR the single most (negatively) impactful penalty-factor on an offense's EPA-performance in a given game. SO, all that is a long way to stay...the league is generally going to be motivated to call LESS holding, not more, unfortunately.
I also think that with guys like Micah or Myles Garrett or the like, to some extent there's almost an issue of them being TOO good. These guys are so head-and-shoulders above most NFL offensive linemen that holding them is the only way to have a fighting chance. If the OT doesn't hold Parsons, he's probably coming away with 6 sacks against Chicago. These guys would hit double-digits some weeks. The QB's going to get killed and the opposing offense is going to do nothing. If you don't hold those guys, offenses get tanked and the opponent's most valuable player is at a way higher risk of injury. They (the league, owners, etc) don't want that. And if you hold them every play to survive and it gets called every play... then games take 6 hours and the offense still never does anything. It's almost like these guys are simply TOO disruptive to be treated fairly in this way.
Which, all that being said, it's a real bummer, because we made a huge investment in draft capital and cash for Parsons to be an absolutely game-wrecking player...while it feels like the league simply does not want games "wrecked" in that sort of way. So, I don't really know what the solution there is.