The defense may be able to slow-down Calvin and the running game sufficiently, but Golden F' in Tate as well as their TE's (Fauria & Ebron) run wild for over 300 yds. combined.
This is possible, but is highly dependent upon one thing: Stafford's level of desperation. In week 1, the Lions could do whatever they wanted against the Giants. Stafford had time to settle down and stick to a game plan. Against the Panthers, he started well. Game was 0-0, and the Lions pretty much moved the ball at will. However, once he found himself in a hole he went all '2013' (heave it as hard as possible to Johnson regardless of coverage, or who else is open).
If the game is close and Stafford remains patient, he can light you up something fierce. He seems to have gained some mobility, so pressuring him doesn't seem to phase him like it used to either. Go up by 2+ scores on him though, and he fixates on CJ.
If you guys go up a score or two quickly on us, my fear is that he will again fixate on CJ. 75% of the time it works out, and we all see it on Sports Center for a week. But that 25% of the time.... INTs galore.......