Denzel Ward is 183 pounds, didn't weigh in at his pro-day and only started one year. He's a gamble.
Saquon Barkley for all of his talent, doesn't possess great vision and doesn't run between the tackles well. He's a gamble.
Quenton Nelson is a great run blocker who can occasionally struggle pass blocking against quick 3T's. He's a gamble.
Sam Darnold for all of his talent, has a problem with turnovers. He's a gamble.
Baker Mayfield is small, not that fast, and doesn't have a big arm. He's a gamble.
Bradley Chubb isn't overly athletic, is better against the run than as a pass rusher, and had a really poor 3-cone time. He's a gamble.
Roquan Smith struggles shedding blockers. He's a gamble.
Tremaine Edmunds is raw and doesn't use his athletic capabilities to their fullest, and might be more athlete than football player. He's a gamble.
I could go on, and on, and on, and on. There are no safe picks. Quenton Nelson is probably as safe as it gets, but we've heard that about iOL before, and they've still done nothing!
My point is that every player in this draft is a risk. Every player is a gamble. That's why most GM's don't have an excellent record in the draft...it's stinking hard! They are all a risk, there is no such thing as a sure thing.