Early in the second quarter Sunday, Houston running back Ahman Green left the game with a left knee injury.
Green, Houston's leading rusher, caught a short pass and was tackled after a nine-yard gain by Colts safety Bob Sanders. Green hopped up, but limped off the field as trainers attended to him on the sideline.
Green hobbled to a training table behind the bench as Kris Brown kicked a 33-yard field goal to put the Texans up 10-7.
On Wednesday, the Texans said Green was limited at practice with a knee injury.
Samkon Gado replaced Green on the Texans' next offensive series. Green sat on the bench with ice wrapped around his left knee.